High-Grade B-Cell Lymphoma, FISH
CPT:
Contact CPT coding department at 800-222-7566, ext. 6-8400.
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Contact CPT coding department at 800-222-7566, ext. 6-8400. |
Test Includes
This test includes fluorescence in situ hybridization (FISH) for high-grade B-cell lymphoma, targeting rearrangement of BCL2, BCL6 and MYC.
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This test includes fluorescence in situ hybridization (FISH) for high-grade B-cell lymphoma, targeting rearrangement of BCL2, BCL6 and MYC. |
Special Instructions
Indicate the pertinent clinical diagnosis and previous cytogenetic studies on the test request form. Note: This test number is used for tracking FISH specimens to the laboratory.
Expected Turnaround Time
3 - 5 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Related Information
Related Documents
Specimen Requirements
Specimen
Blood, bone marrow, slides, paraffin block, lymph node or touch preps
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Blood, bone marrow, slides, paraffin block, lymph node |
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Blood, bone marrow, slides, paraffin block, lymph node or touch preps |
Volume
7 mL blood (adult), 1-3 mL bone marrow, five slides from cytogenetic analysis or seven slides from paraffin block, one tube fixed pellet, 4 touch prep slides
Minimum Volume
1 mL blood, 1 mL bone marrow, and four- to five-micron FFPE slides, 5 touch prep slides
Container
Green-top (sodium heparin) tube; pediatric Vacutainer® is optimal or lavender-top (EDTA) tube
Storage Instructions
Maintain specimens at room temperature.
Causes for Rejection
Broken Vacutainer®; broken slides
Test Details
Use
This test is a diagnostic test for non-Hodgkin's lymphoma (NHL) that detects primary genetic changes associated with various types of NHL, including high-grade B-cell lymphoma, follicular lymphoma (FL), Burkitt lymphoma (BL), diffuse large B-cell lymphoma (DLBCL) and those with BCL6 rearrangement.
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This test is a diagnostic test for non-Hodgkin's lymphoma (NHL) that detects primary genetic changes associated with various types of NHL, including high-grade B-cell lymphoma, follicular lymphoma (FL), Burkitt lymphoma (BL), diffuse large B-cell lymphoma (DLBCL) and those with BCL6 rearrangement. |
Limitations
Molecular mutations below the resolution of FISH will not be detected.
Methodology
Fluorescence in situ hybridization (FISH)
LOINC® Map
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