Autoimmune Myelopathy Profile, Spinal Fluid
CPT:
84182; 86052; 86255(x14); 86341; 86362
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84182; 86052; 86255(x14); 86341; 86362 |
| 84182; 86052; 86255(x14); 86341; 8636284182; 86052; 86255(x14); 86341; 86362 |
Special Instructions
If reflex test is performed, additional charges/CPT code(s) may apply.
Expected Turnaround Time
3 - 5 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
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3 - 5 days |
Related Documents
Specimen Requirements
Specimen
Cerebrospinal fluid (CSF)
Volume
2 mL
Minimum Volume
1 mL (Note: This volume does not allow for repeat testing.)
Container
Sterile screw capped vial
Collection
Do not centrifuge cerebrospinal fluid.
Storage Instructions
Room temperature
Stability Requirements
Temperature | Period |
|---|---|
Room temperature | 14 days |
Refrigerated | 14 days |
Frozen | 14 days |
Freeze/thaw cycles | Stable x3 |
Test Details
Use
This test can assist in the diagnosis (paraneoplastic or idiopathic autoimmune) and aid distinction from other causes of myelopathy (sarcoidosis, vascular disease, multiple sclerosis). Early testing may assist in early diagnosis of occult cancer, prompt initiation of immune therapies, or both.
Limitations
This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.
Methodology
Immunofluorescence (IFA), line blot
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 505409 | Autoimmune Myelopathy, CSF | 94353-0 | 505562 | Interpretation | 56850-1 | |
| 505409 | Autoimmune Myelopathy, CSF | 94353-0 | 505611 | Anti-Hu Ab | 44768-0 | |
| 505409 | Autoimmune Myelopathy, CSF | 94353-0 | 505612 | Anti-Ri Ab | 56959-0 | |
| 505409 | Autoimmune Myelopathy, CSF | 94353-0 | 505613 | Antineuronal nuclear Ab Type 3 | 90836-8 | |
| 505409 | Autoimmune Myelopathy, CSF | 94353-0 | 505616 | PCA Type-1 (Anti-Yo) Ab | 14247-1 | |
| 505409 | Autoimmune Myelopathy, CSF | 94353-0 | 505617 | Purkinje Cell Cyto Ab Type 2 | 90843-4 | |
| 505409 | Autoimmune Myelopathy, CSF | 94353-0 | 505618 | Purkinje Cell Cyto Ab Type Tr | 90845-9 | |
| 505409 | Autoimmune Myelopathy, CSF | 94353-0 | 505619 | Amphiphysin Antibody | 90815-2 | |
| 505409 | Autoimmune Myelopathy, CSF | 94353-0 | 505621 | CRMP-5 IgG | 63216-6 | |
| 505409 | Autoimmune Myelopathy, CSF | 94353-0 | 505622 | CRMP-5 IgG Line Blot | 53707-6 | |
| 505409 | Autoimmune Myelopathy, CSF | 94353-0 | 505623 | AGNA-1 | 90827-7 | |
| 505409 | Autoimmune Myelopathy, CSF | 94353-0 | 505624 | DPPX Antibody | 82989-5 | |
| 505409 | Autoimmune Myelopathy, CSF | 94353-0 | 505626 | mGluR1 Antibody | 93500-7 | |
| 505409 | Autoimmune Myelopathy, CSF | 94353-0 | 505593 | AMPA-R-2 Cell-based IFA | 93491-9 | |
| 505409 | Autoimmune Myelopathy, CSF | 94353-0 | 505597 | GABA-B Receptor Cell-based IFA | 93426-5 | |
| 505409 | Autoimmune Myelopathy, CSF | 94353-0 | 505599 | NMDAR Antibody, Cell-based IFA | 82988-7 | |
| 505409 | Autoimmune Myelopathy, CSF | 94353-0 | 505704 | GAD65 Antibody, Cell-based IFA | 94711-9 | |
| 505409 | Autoimmune Myelopathy, CSF | 94353-0 | 505757 | Anti-AQP4, CSF, Cell-based IFA | 90818-6 | |
| 505409 | Autoimmune Myelopathy, CSF | 94353-0 | 505777 | Anti-MOG, CSF, Cell-based IFA | 91543-9 |
| Reflex Table for Anti-Hu Ab | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 505563 | Anti-Hu Ab Line Blot | 505563 | Anti-Hu Ab Line Blot | Pending | |
| Reflex Table for Anti-Ri Ab | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 505564 | Anti-Ri Ab Line Blot | 505564 | Anti-Ri Ab Line Blot | Pending | |
| Reflex Table for PCA Type-1 (Anti-Yo) Ab | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 505566 | Anti-Yo Ab Line Blot | 505566 | Anti-Yo Ab Line Blot | Pending | |
| Reflex Table for Purkinje Cell Cyto Ab Type Tr | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 505567 | PCA-Tr Line Blot | 505567 | PCA-Tr Line Blot | Pending | |
| Reflex Table for Amphiphysin Antibody | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 505568 | Amphiphysin Line Blot | 505568 | Amphiphysin Line Blot | Pending | |
| Reflex Table for CRMP-5 IgG | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 505622 | CRMP-5 IgG Line Blot | 505622 | CRMP-5 IgG Line Blot | 53707-6 | |
| Reflex Table for AGNA-1 | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 505569 | AGNA-1 Line Blot | 505569 | AGNA-1 Line Blot | Pending | |
| Reflex Table for DPPX Antibody | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 505571 | DPPX Cell-based IFA | 505571 | DPPX Cell-based IFA | Pending | |
| Reflex 2 | 505572 | DPPX Antibody, Titer | 505572 | DPPX Antibody, Titer | Pending | |
| Reflex Table for mGluR1 Antibody | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 505574 | mGluR1 Cell-based IFA | 505574 | mGluR1 Cell-based IFA | 93498-4 | |
| Reflex 2 | 505576 | mGluR1 IF Titer | 505576 | mGluR1 IF Titer | 93499-2 | |
| Reflex Table for AMPA-R-2 Cell-based IFA | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 505596 | AMPA-R-2 IF Titer | 505596 | AMPA-R-2 IF Titer | Pending | |
| Reflex Table for GABA-B Receptor Cell-based IFA | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 505598 | GABA-B Receptor Antibody Titer | 505598 | GABA-B Receptor Antibody Titer | Pending | |
| Reflex Table for NMDAR Antibody, Cell-based IFA | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 505606 | Anti-NMDAR Antibody Titer | 505606 | Anti-NMDAR Antibody Titer | Pending | |
| Reflex Table for GAD65 Antibody, Cell-based IFA | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 505691 | Anti-GAD65 Antibody Titer | 505691 | Anti-GAD65 Antibody Titer | Pending | |
| Reflex Table for Anti-AQP4, CSF, Cell-based IFA | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 505759 | Anti-AQP4 Antibody, CSF, Titer | 505759 | Anti-AQP4 Antibody, CSF, Titer | 90819-4 | |
| Reflex Table for Anti-MOG, CSF, Cell-based IFA | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 505778 | Anti-MOG, CSF, Titer | 505778 | Anti-MOG, CSF, Titer | 91542-1 | |
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The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf