Synonyms
- Insulin Resistance Syndrome
- Reaven's Syndrome
- Syndrome X
Test Includes
Glucose, plasma; HDL cholesterol; triglycerides
Expected Turnaround Time
Within 1 day
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Related Documents
Specimen Requirements
Specimen
Serum and plasma
Volume
1 mL serum and 0.5 mL plasma
Minimum Volume
0.5 mL serum and 0.5 mL plasma (Note: This volume does not allow for repeat testing.)
Container
Gel-barrier tube, transport tube, or green-top (heparin) tube and gray-top (sodium fluoride) tube
Collection
Separate serum or plasma from cells within 45 minutes of collection. Label gray-top tube as plasma.
Storage Instructions
Maintain specimen at room temperature.
Stability Requirements
Temperature | Period |
|---|---|
Room temperature | 3 days |
Refrigerated | 14 days |
Frozen | 14 days |
Freeze/thaw cycles | Stable x2 |
Patient Preparation
Patient should be fasting for 12 to 14 hours and on a stable diet for two weeks prior to blood collection.
Causes for Rejection
Gross hemolysis; nonfasting specimen; specimen collected in glycerin tube; improper labeling
Test Details
Use
Identify individuals with metabolic syndrome. The National Cholesterol Education Program, Adult Treatment Panel III guidelines indicate that metabolic syndrome is present in patients with any three of the following five symptoms:
• HDL <40 mg/dL in men and <50 mg/dL in women
• Triglycerides ≥150 mg/dL
• Glucose ≥110 mg/dL
• Blood pressure ≥130/85
• Waist circumference >40” in men and >35” in women
Metabolic syndrome conveys an increased risk of diabetes, hypertension, gallbladder disease, osteoarthritis, and cardiovascular disease.
Limitations
This profile should not be performed on patients who have, in the preceding three months, suffered a myocardial infarction or similar traumatic episode, including acute infection or inflammation.
Methodology
Enzymatic
References
Mokdad AH, Ford ES, Bowman BA, et al. Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001. JAMA. 2003 Jan 1; 289(1):76-79.12503980
National Heart, Lung, and Blood Institute. Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Bethesda, Md: National Heart, Lung, and Blood Institute, National Institutes of Health; 2001. NIH Publication 02-5215.
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 335884 | Metabolic Syndrome Profile | 49898-0 | 001820 | Glucose, Plasma | mg/dL | 2345-7 |
| 335884 | Metabolic Syndrome Profile | 49898-0 | 001174 | Triglycerides | mg/dL | 2571-8 |
| 335884 | Metabolic Syndrome Profile | 49898-0 | 011820 | HDL Cholesterol | mg/dL | 2085-9 |
| 335884 | Metabolic Syndrome Profile | 49898-0 | 001821 | See below: | N/A |
| Reflex Table for HDL Cholesterol | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 011819 | Comment | 011819 | Comment | N/A | |
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The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf