Synonyms
- Anidulafungin Antifungal AST
- Fungal AST
- Fungal Susceptibility Testing
Test Includes
Susceptibility testing of a yeast isolate to anidulafungin
Expected Turnaround Time
4 - 10 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Related Documents
Specimen Requirements
Specimen
Yeast isolated from a primary clinical specimen on a submitted mycological or bacterial medium
Volume
Pure culture yeast isolate on solid medium
Container
Solid medium, tightly sealed, in etiologic agent packaging
Storage Instructions
Maintain media at room temperature.
Causes for Rejection
Isolate nonviable; yeast isolate other than Candida species (e.g., Cryptococcus species); non-yeast isolate (e.g., bacteria or mold); unlabeled specimen or name discrepancy between specimen and request label
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Isolate nonviable; yeast isolate other than Candida species (e.g., Cryptococcus species); non-yeast isolate (e.g., bacteria or mold); unlabeled specimen or name discrepancy between specimen and request label |
Test Details
Use
This test is used to determine the susceptibility of yeast isolates to antifungal agents.
Interpretive criteria are provided for certain organism/drug combinations based on clinical data from infections with Candida spp. Note that the intermediate category provides a buffer zone to limit errors associated with inherent variability in the test method. Strains with intermediate MICs might respond clinically to a higher-than-standard dose of a drug or in situations in which drug penetration is maximized.
Limitations
Susceptibilities cannot be reported if the organism fails to grow in the test medium. Susceptibilities cannot be performed on mixed cultures.
This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.
Methodology
Microbroth dilution/minimum inhibitory concentration (MIC)
References
Clinical and Laboratory Standards Institute (CLSI). Performance Standards for Antifungal Susceptibility Testing of Yeasts. 3rd ed. CLSI supplement M27M44S. CLSI; 2022.
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