Varicella Zoster Virus (VZV) IgG, Immunity Status
CPT:
To be determined. Updates will be made when available.
Synonyms
Chickenpox
Specimen Requirements
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.2 mL
Container
Red-top tube or gel-barrier tube
Collection
If a tube other than a gel-barrier tube is used, transfer separated serum to a plastic transport tube. Do not freeze gel-barrier tube (pour off serum first).
Storage Instructions
Room temperature
Stability Requirements
| Temperature | Period |
|---|---|
| Room temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |
| Freeze/thaw cycles | Stable x4 |
Causes for Rejection
Hemolysis; lipemia; gross bacterial contamination
Test Details
Use
This test is used to determine the immune status of individuals to the varicella zoster virus (VZV) and offer documentation of previous infection with VZV in an individual without a documented history of completion of the VZV vaccination series.
Limitations
Routine testing for varicella immunity following vaccination is unnecessary because commercially available VZV IgG assays are not sensitive enough to detect all seroconversions after a vaccination.
Methodology
Chemiluminescent immunoassay (CLIA)
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