UKEMS 2023 -- The in vivo phosphatidylinositol glycan class A (Pig-a) gene mutation assay is based on the endogenous X-linked Pig-a gene, which codes for an N-acetyl glucosamine transferase that is involved in the biosynthesis of glycosyl phosphatidyl inositol (GPI) anchor for tethering a variety of mammalian cell surface protein markers.

UKEMS 2023 -- The Bhas 42 cell promoter transformation assay is a sensitive short-term system for predicting chemical carcinogenicity related to transformation promotion activity. Bhas 42 cells were established from BALB/c 3T3 A31-1-1 cells by the transfection of v‑Ha‑ras gene.

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