STP 2022 -- Historical control data are important tools used in toxicologic pathology for the evaluation and interpretation of neoplastic and nonneoplastic findings reported during rodent carcinogenicity studies.
Large clinical trials demand experience managing complex organizational requirements to synchronize many moving parts. In the past, Labcorp Drug Development has successfully conducted 14 global mega-trials involving cardiovascular outcomes.
CF remains one of the most common life-shortening inherited diseases, despite breakthroughs in targeted therapies in recent years. Research and development efforts continue, but those involved face major challenges in finding specialized trial sites and enrolling enough eligible patients.
Your drug candidate has potential to become the next medical breakthrough. When your studies need support in overcoming operational challenges, we can scale our customizable staffing service to best fit your needs and budget.
For some patients living with cancer, clinical trials may provide new treatment avenues when they fail to respond to standard of care treatment or experience recurrence of their cancer after treatment.
UKEMS 2022 -- The ToxTracker® Assay is a panel of mouse embryonic stem cells (mES) with pathways tagged via green fluorescent protein (GFP) such that the biological reactivity and potential carcinogenic properties of novel substances can be identified. The panel of biomarkers was established following extensive genome-wide transcription profiling.
UKEMS 2022 -- Lung inflammation plays a role in the pathogenesis of various respiratory diseases such as asthma and chronic obstructive pulmonary disorder (COPD). The etiology of these diseases involves interactions between lung and immune cells, with immune cells regulating the body's response to external stimuli.
UKEMS 2022 -- The in vivo Pig-a gene mutation assay is based on the endogenous X-linked Pig-a gene, which codes for an N-acetyl glucosamine transferase that is involved in the biosynthesis of Glycosyl Phosphatidyl Inositol (GPI) anchor for tethering a variety of mammalian cell surface protein markers.