Test Details
Methodology
Enzyme-linked immunosorbent assay (ELISA)
Result Turnaround Time
7 - 10 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Use
Anti-DFS70 antibodies may help identify individuals who do not have an ANA-associated Autoimmune Rheumatic Disease (AARD) especially in the absence of significant clinical findings.1 Anti-DFS70 Ab, especially when positive in isolation (i.e. in the absence of AARD-associated autoantibodies), may prevent unnecessary referrals and examinations of ANA-positive individuals.2
Limitations
This test should be used with clinical findings and other autoimmune testing; it cannot be used alone to rule out autoimmune disease.
This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.
Custom Additional Information
Anti-DFS70 antibodies target the dense fine speckled protein of 70 kDa which is identical to Lens Epithelium-Derived Growth Factor or transcription co-activator p75 (LEDGFp75). They are detectable in 2% to 22% of healthy individuals and in less than 1% of patients with AARD are of unknown clinical significance.
Specimen Requirements
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Red-top tube; serum from red-top tube; serum from a gel tube; or serum gel tube
Collection Instructions
Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping.
Stability Requirements
| Temperature | Period |
|---|---|
| Room temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |
| Freeze/thaw cycles | Stable x3 |
Storage Instructions
Refrigerate or freeze.
Footnotes
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 520313 | Anti-DFS70 Ab | 95129-3 | 520314 | Anti-DFS70 Ab | Units | 95129-3 |
| Order Code | 520313 | |||||
| Order Code Name | Anti-DFS70 Ab | |||||
| Order Loinc | 95129-3 | |||||
| Result Code | 520314 | |||||
| Result Code Name | Anti-DFS70 Ab | |||||
| UofM | Units | |||||
| Result LOINC | 95129-3 |