Synonyms
- ANCA Profile
- Anti-Neutrophil Cytoplasmic Panel
Test Includes
ANCA; Anti-MPO (Myeloperoxidase) Ab; Anti-PR-3 (Proteinase 3) Ab; c-ANCA ans p-ANCA are resulted if positive. Otherwise, ANCA is reported as negative. Anti-Nuclear Ab (ANA) by IFA is performed if ANCA positive.
Expected Turnaround Time
7 - 10 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Related Documents
Specimen Requirements
Specimen
Serum
Volume
3 mL
Minimum Volume
2 mL (Note: This volume does not allow for repeat testing.)
Container
Red-top tube or gel-barrier tube
Collection
Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping.
Storage Instructions
Refrigerate.
Stability Requirements
Temperature | Period |
|---|---|
Room temperature | 7 days |
Refrigerated | 14 days |
Frozen | 60 days |
Freeze/thaw cycles | Stable x1 |
Causes for Rejection
Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types
Test Details
Use
C-ANCA & P-ANCA resulted if positive, otherwise reported as ANCA Negative. PANCA confirmed on formalin fixed slides. ANA performed if ANCA positive to rule out false positive ANCA due to presence of ANA.
Limitations
This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.
Methodology
Enzyme-linked immunosorbent assay (ELISA); Indirect fluorescent antibody (IFA)
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 520149 | ANCA Profile (RDL) | 520150 | ANCA by IFA (RDL) | 29641-8 | ||
| 520149 | ANCA Profile (RDL) | 520154 | Anti-MPO Ab (RDL) | Units | 72515-0 | |
| 520149 | ANCA Profile (RDL) | 520155 | Anti-PR-3 Ab (RDL) | Units | 63311-5 |
| Reflex Table for ANCA by IFA (RDL) | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 520245 | Positive ANCA Reflex | 520187 | C-ANCA (IFA-ETOH) | 14277-8 | |
| Reflex Table for ANCA by IFA (RDL) | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 520245 | Positive ANCA Reflex | 520189 | P-ANCA (IFA-ETOH) | 14278-6 | |
| Reflex Table for ANCA by IFA (RDL) | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 520245 | Positive ANCA Reflex | 520191 | P-ANCA (IFA-Formalin) | 17357-5 | |
| Reflex Table for ANCA by IFA (RDL) | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 520245 | Positive ANCA Reflex | 520073 | Anti-Nuclear Ab by IFA (RDL) | 42254-3 | |
| Reflex 2 | 520248 | ANA Panel for ANCA | 520074 | Homogeneous Pattern | 20398-4 | |
| Reflex Table for ANCA by IFA (RDL) | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 520245 | Positive ANCA Reflex | 520073 | Anti-Nuclear Ab by IFA (RDL) | 42254-3 | |
| Reflex 2 | 520248 | ANA Panel for ANCA | 520076 | Nucleolar Pattern | 20399-2 | |
| Reflex Table for ANCA by IFA (RDL) | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 520245 | Positive ANCA Reflex | 520073 | Anti-Nuclear Ab by IFA (RDL) | 42254-3 | |
| Reflex 2 | 520248 | ANA Panel for ANCA | 520233 | Speckled Pattern | 20401-6 | |
| Reflex Table for ANCA by IFA (RDL) | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 520245 | Positive ANCA Reflex | 520073 | Anti-Nuclear Ab by IFA (RDL) | 42254-3 | |
| Reflex 2 | 520248 | ANA Panel for ANCA | 520234 | Centromere Pattern | 53993-2 | |
| Reflex Table for ANCA by IFA (RDL) | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 520245 | Positive ANCA Reflex | 520073 | Anti-Nuclear Ab by IFA (RDL) | 42254-3 | |
| Reflex 2 | 520248 | ANA Panel for ANCA | 520235 | Spindle Apparatus Pattern | 53003-0 | |
| Reflex Table for ANCA by IFA (RDL) | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 520245 | Positive ANCA Reflex | 520073 | Anti-Nuclear Ab by IFA (RDL) | 42254-3 | |
| Reflex 2 | 520248 | ANA Panel for ANCA | 520236 | Nuclear Membrane Pattern | 54006-2 | |
| Reflex Table for ANCA by IFA (RDL) | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 520245 | Positive ANCA Reflex | 520073 | Anti-Nuclear Ab by IFA (RDL) | 42254-3 | |
| Reflex 2 | 520248 | ANA Panel for ANCA | 520237 | Midbody Pattern | 54155-7 | |
| Reflex Table for ANCA by IFA (RDL) | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 520245 | Positive ANCA Reflex | 520073 | Anti-Nuclear Ab by IFA (RDL) | 42254-3 | |
| Reflex 2 | 520248 | ANA Panel for ANCA | 520238 | Nuclear Dot Pattern | 53998-1 | |
| Reflex Table for ANCA by IFA (RDL) | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 520245 | Positive ANCA Reflex | 520073 | Anti-Nuclear Ab by IFA (RDL) | 42254-3 | |
| Reflex 2 | 520248 | ANA Panel for ANCA | 520239 | PCNA Pattern | 53006-3 | |
| Reflex Table for ANCA by IFA (RDL) | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 520245 | Positive ANCA Reflex | 520073 | Anti-Nuclear Ab by IFA (RDL) | 42254-3 | |
| Reflex 2 | 520248 | ANA Panel for ANCA | 520240 | Centriole Pattern | 53993-2 | |
| Reflex Table for ANCA by IFA (RDL) | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 520245 | Positive ANCA Reflex | 520073 | Anti-Nuclear Ab by IFA (RDL) | 42254-3 | |
| Reflex 2 | 520248 | ANA Panel for ANCA | 520241 | Note: | 77202-0 | |
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