Test Details
Methodology
Multiplex bead-based immunoassay and Meso Scale Discovery Multi-array Platform
Result Turnaround Time
6 - 8 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Use
Vectra® measures 12 biomarkers and incorporates age, gender and adiposity in adult
patients with rheumatoid arthritis (RA) to provide a single score that is an objective measure of
inflammation, which reflects disease activity, predicts risk of radiographic progression and
informs medical management decisions designed to prevent irreversible joint damage. The 12
biomarkers required to generate a Vectra® Score are VCAM-1, EGF, VEGF-A, IL-6, TNF-RI, MMP1,
MMP3, YKL-40, Leptin, Resistin, SAA and CRP.
Specimen Requirements
Specimen
Serum
Volume
2 mL
Minimum Volume
1 mL
Container
Gel-barrier tube, red-top tube or serum transfer tube
Collection Instructions
Allow specimen to clot for 30 minutes. Centrifuge and separate from cells within 45 minutes of draw. Transfer to a plastic transport tube before shipping.
Stability Requirements
| Temperature | Period |
|---|---|
| Room temperature | 3 days |
| Refrigerated | 14 days |
| Frozen | 326 days |
Storage Instructions
Ship on frozen cool packs or dry ice. Ship with enough dry ice so ice exists upon receipt of package. Samples cannot go above room temperature.
Causes for Rejection
Gross hemolysis; gross lipemia; improper labeling; patients less than 18 years old or more than 100 years old
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 504965 | Vectra(R) | 75635-3 | 504966 | Vectra Score | 75633-8 | |
| 504965 | Vectra(R) | 75635-3 | 504967 | Risk of Radiographic Progress | % | N/A |
| 504965 | Vectra(R) | 75635-3 | 504969 | Vectra(R) Level | 75634-6 | |
| 504965 | Vectra(R) | 75635-3 | 504968 | Test Description | N/A | |
| 504965 | Vectra(R) | 75635-3 | 504973 | SAA Result | ug/mL | 1847-3 |
| 504965 | Vectra(R) | 75635-3 | 504974 | CRP Result | mg/L | 1988-5 |
| 504965 | Vectra(R) | 75635-3 | 504975 | VCAM-1 Result | ug/mL | 75627-0 |
| 504965 | Vectra(R) | 75635-3 | 504976 | IL-6 Result | pg/mL | 26881-3 |
| 504965 | Vectra(R) | 75635-3 | 504977 | TNF-RI Result | ng/mL | 75629-6 |
| 504965 | Vectra(R) | 75635-3 | 504978 | EGF Result | pg/mL | 14049-1 |
| 504965 | Vectra(R) | 75635-3 | 504979 | VEGF-A Result | pg/mL | 75628-8 |
| 504965 | Vectra(R) | 75635-3 | 504981 | Leptin Result | ng/mL | 21365-2 |
| 504965 | Vectra(R) | 75635-3 | 504982 | Resistin Result | ng/mL | 75632-0 |
| 504965 | Vectra(R) | 75635-3 | 504983 | MMP-1 Result | ng/mL | 75630-4 |
| 504965 | Vectra(R) | 75635-3 | 504984 | MMP3 Result | ng/mL | 75631-2 |
| 504965 | Vectra(R) | 75635-3 | 504985 | YKL-40 Result | ng/mL | 48663-9 |
| 504965 | Vectra(R) | 75635-3 | 504999 | Biomarker Comment: | N/A | |
| 504965 | Vectra(R) | 75635-3 | 504986 | Footnote/History | N/A | |
| 504965 | Vectra(R) | 75635-3 | 504970 | Clinical Validation | N/A | |
| 504965 | Vectra(R) | 75635-3 | 504997 | Vectra(R) PDF | 11502-2 | |
| Order Code | 504965 | |||||
| Order Code Name | Vectra(R) | |||||
| Order Loinc | 75635-3 | |||||
| Result Code | 504966 | |||||
| Result Code Name | Vectra Score | |||||
| UofM | ||||||
| Result LOINC | 75633-8 | |||||
| Order Code | 504965 | |||||
| Order Code Name | Vectra(R) | |||||
| Order Loinc | 75635-3 | |||||
| Result Code | 504967 | |||||
| Result Code Name | Risk of Radiographic Progress | |||||
| UofM | % | |||||
| Result LOINC | N/A | |||||
| Order Code | 504965 | |||||
| Order Code Name | Vectra(R) | |||||
| Order Loinc | 75635-3 | |||||
| Result Code | 504969 | |||||
| Result Code Name | Vectra(R) Level | |||||
| UofM | ||||||
| Result LOINC | 75634-6 | |||||
| Order Code | 504965 | |||||
| Order Code Name | Vectra(R) | |||||
| Order Loinc | 75635-3 | |||||
| Result Code | 504968 | |||||
| Result Code Name | Test Description | |||||
| UofM | ||||||
| Result LOINC | N/A | |||||
| Order Code | 504965 | |||||
| Order Code Name | Vectra(R) | |||||
| Order Loinc | 75635-3 | |||||
| Result Code | 504973 | |||||
| Result Code Name | SAA Result | |||||
| UofM | ug/mL | |||||
| Result LOINC | 1847-3 | |||||
| Order Code | 504965 | |||||
| Order Code Name | Vectra(R) | |||||
| Order Loinc | 75635-3 | |||||
| Result Code | 504974 | |||||
| Result Code Name | CRP Result | |||||
| UofM | mg/L | |||||
| Result LOINC | 1988-5 | |||||
| Order Code | 504965 | |||||
| Order Code Name | Vectra(R) | |||||
| Order Loinc | 75635-3 | |||||
| Result Code | 504975 | |||||
| Result Code Name | VCAM-1 Result | |||||
| UofM | ug/mL | |||||
| Result LOINC | 75627-0 | |||||
| Order Code | 504965 | |||||
| Order Code Name | Vectra(R) | |||||
| Order Loinc | 75635-3 | |||||
| Result Code | 504976 | |||||
| Result Code Name | IL-6 Result | |||||
| UofM | pg/mL | |||||
| Result LOINC | 26881-3 | |||||
| Order Code | 504965 | |||||
| Order Code Name | Vectra(R) | |||||
| Order Loinc | 75635-3 | |||||
| Result Code | 504977 | |||||
| Result Code Name | TNF-RI Result | |||||
| UofM | ng/mL | |||||
| Result LOINC | 75629-6 | |||||
| Order Code | 504965 | |||||
| Order Code Name | Vectra(R) | |||||
| Order Loinc | 75635-3 | |||||
| Result Code | 504978 | |||||
| Result Code Name | EGF Result | |||||
| UofM | pg/mL | |||||
| Result LOINC | 14049-1 | |||||
| Order Code | 504965 | |||||
| Order Code Name | Vectra(R) | |||||
| Order Loinc | 75635-3 | |||||
| Result Code | 504979 | |||||
| Result Code Name | VEGF-A Result | |||||
| UofM | pg/mL | |||||
| Result LOINC | 75628-8 | |||||
| Order Code | 504965 | |||||
| Order Code Name | Vectra(R) | |||||
| Order Loinc | 75635-3 | |||||
| Result Code | 504981 | |||||
| Result Code Name | Leptin Result | |||||
| UofM | ng/mL | |||||
| Result LOINC | 21365-2 | |||||
| Order Code | 504965 | |||||
| Order Code Name | Vectra(R) | |||||
| Order Loinc | 75635-3 | |||||
| Result Code | 504982 | |||||
| Result Code Name | Resistin Result | |||||
| UofM | ng/mL | |||||
| Result LOINC | 75632-0 | |||||
| Order Code | 504965 | |||||
| Order Code Name | Vectra(R) | |||||
| Order Loinc | 75635-3 | |||||
| Result Code | 504983 | |||||
| Result Code Name | MMP-1 Result | |||||
| UofM | ng/mL | |||||
| Result LOINC | 75630-4 | |||||
| Order Code | 504965 | |||||
| Order Code Name | Vectra(R) | |||||
| Order Loinc | 75635-3 | |||||
| Result Code | 504984 | |||||
| Result Code Name | MMP3 Result | |||||
| UofM | ng/mL | |||||
| Result LOINC | 75631-2 | |||||
| Order Code | 504965 | |||||
| Order Code Name | Vectra(R) | |||||
| Order Loinc | 75635-3 | |||||
| Result Code | 504985 | |||||
| Result Code Name | YKL-40 Result | |||||
| UofM | ng/mL | |||||
| Result LOINC | 48663-9 | |||||
| Order Code | 504965 | |||||
| Order Code Name | Vectra(R) | |||||
| Order Loinc | 75635-3 | |||||
| Result Code | 504999 | |||||
| Result Code Name | Biomarker Comment: | |||||
| UofM | ||||||
| Result LOINC | N/A | |||||
| Order Code | 504965 | |||||
| Order Code Name | Vectra(R) | |||||
| Order Loinc | 75635-3 | |||||
| Result Code | 504986 | |||||
| Result Code Name | Footnote/History | |||||
| UofM | ||||||
| Result LOINC | N/A | |||||
| Order Code | 504965 | |||||
| Order Code Name | Vectra(R) | |||||
| Order Loinc | 75635-3 | |||||
| Result Code | 504970 | |||||
| Result Code Name | Clinical Validation | |||||
| UofM | ||||||
| Result LOINC | N/A | |||||
| Order Code | 504965 | |||||
| Order Code Name | Vectra(R) | |||||
| Order Loinc | 75635-3 | |||||
| Result Code | 504997 | |||||
| Result Code Name | Vectra(R) PDF | |||||
| UofM | ||||||
| Result LOINC | 11502-2 |