Multiple Sclerosis Monitoring Profile
CPT:
To be determined. Updates will be made when available.
Test Includes
Glial Fibrillary Acid Protein, Serum; GFAP, Serum Z Score; Neurofilament Light Chain, Serum; NFL, Serum Z Score
Expected Turnaround Time
1 - 3 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Specimen Requirements
Specimen
Serum
Volume
2 mL
Minimum Volume
1 mL (Note: This volume does not allow for repeat testing.)
Container
Gel-barrier tube (preferred) or red-top tube
Collection
If a red-top tube is used, transfer separated serum to a plastic transport tube.
Storage Instructions
Room temperature
Stability Requirements
| Temperature | Period |
|---|---|
| Room temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |
| Freeze/thaw cycle | Stable x3 |
Test Details
Use
This test is used to monitor Neurofilament Light Chain, Serum (NfL) and Glial Fibrillary Acid Protein, Serum (GFAP) values in multiple sclerosis patients.
Limitations
This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.
Methodology
Roche Diagnostics Electrochemiluminescence Immunoassay (ECLIA)
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CPT Statement/Profile Statement
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