查找地点
有关时间、上门服务和预约查找地点
有关时间、上门服务和预约Reflex to qualitative rapid plasma reagin (RPR) on positives
1 - 4 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Serum
1 mL
0.5 mL (Note: This volume does not allow for repeat testing.)
Red-top tube or gel-barrier tube
Room temperature
Temperature | Period |
---|---|
Room temperature | 14 days |
Refrigerated | 14 days |
Frozen | 14 days |
Freeze/thaw cycles | Stable x3 |
Hemolysis; lipemia; gross bacterial contamination; plasma specimen
This test is intended to support screening and diagnosis of syphilis infections. This test aligns with the CDC-supported reverse serologic testing algorithm for syphilis using a combination of both treponemal and nontreponemal antibody tests. The reverse syphilis testing algorithm begins with a treponemal antibody assay. Positive samples reflex to RPR (nontreponemal). If the RPR is positive, RPR titer will be determined. If the RPR is negative, a second treponemal antibody assay will be performed to confirm the presence of treponemal antibodies. Interpretation of results obtained must take into account patient symptoms and clinical history.
Treponemal antibodies typically persist for life despite treatment; thus, this assay cannot be used to monitor response to treatment or to assess treatment outcomes. False positive treponemal antibody results have been observed in individuals with nonsyphilis treponemal infections (bejel, pinta, yaws).
Enzyme immunoassay (EIA) with reflex to charcoal flocculation if reactive
Treponemal antibody (CIA) | RPR | RPR titer | Treponemal antibody (EIA) | Interpretation |
---|---|---|---|---|
Nonreactive | Not done | Not done | Not done | No laboratory evidence of syphilis. If recent exposure is suspected, submit a new sample for testing in 2-4 weeks. |
Reactive | Nonreactive | Not done | Nonreactive | Treponemal antibodies not confirmed. Inconclusive for syphilis; potentially early syphilis, possible false positive. If recent exposure is suspected, submit a new sample for testing in 2-4 weeks. If clinical suspicion is low no further evaluation is necessary. |
Reactive | Nonreactive | Not done | Reactive | Treponemal antibodies detected. Consistent with past or current (potentially early) syphilis. Clinical evaluation should be performed to identify current signs and symptoms or past history of infection. If past history of treatment reported, no further management is needed unless symptomatic or recent exposure suspected. If no symptoms or past history of treatment, and if recent exposure is suspected, submit a new sample for testing in 2-4 weeks. |
Reactive | Reactive | 1:1 or greater | Not done | Treponemal and nontreponemal antibodies detected. Consistent with past or current syphilis. Clinical evaluation should be performed to identify current signs and symptoms or past history of infection. |
Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
---|---|---|---|---|---|---|
082345 | T pallidum Screening Cascade | 47236-5 | 082356 | T pallidum Antibodies | 47236-5 |
Reflex Table for T pallidum Antibodies | ||||||
---|---|---|---|---|---|---|
Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
Reflex 1 | 006099 | RPR | 006097 | RPR | 20507-0 | |
Reflex 2 | 006476 | RPR, Quant | 006476 | RPR, Quant | titer | 31147-2 |
Reflex Table for T pallidum Antibodies | ||||||
---|---|---|---|---|---|---|
Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
Reflex 1 | 006099 | RPR | 006097 | RPR | 20507-0 | |
Reflex 2 | 082348 | Treponemal Antibodies, TPPA | 082349 | Treponemal Antibodies, TPPA | 24312-1 |
Reflex Table for T pallidum Antibodies | ||||||
---|---|---|---|---|---|---|
Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
Reflex 1 | 006099 | RPR | 006097 | RPR | 20507-0 | |
Reflex 2 | 082348 | Treponemal Antibodies, TPPA | 010003 | Interpretation: | N/A |
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