Test Details
Methodology
Electrochemiluminescence Immunoassay
Result Turnaround Time
5 - 12 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Test Includes
This test includes serial monitoring.
Limitations
Failure of golimumab therapy may not always be due to the presence of anti-golimumab antibodies. Conversely, the absence of anti-golimumab antibodies does not guarantee response to treatment.
High serum biotin concentrations in patients taking biotin supplements may cause an interference in this assay. Patients may be advised to stop biotin consumption at least 72 hours prior to sample collection.
Failure of golimumab therapy may not always be due to the presence of anti-golimumab antibodies. Conversely, the absence of anti-golimumab antibodies does not guarantee response to treatment. |
Failure of golimumab therapy may not always be due to the presence of anti-golimumab antibodies. Conversely, the absence of anti-golimumab antibodies does not guarantee response to treatment. High serum biotin concentrations in patients taking biotin supplements may cause an interference in this assay. Patients may be advised to stop biotin consumption at least 72 hours prior to sample collection. |
Specimen Requirements
Specimen
Serum or plasma (EDTA)
Volume
3.0 mL
Minimum Volume
1.0 mL
Container
Serum-gel tube, red-top tube, or lavender-top (EDTA) tube
Collection Instructions
Serum/plasma must be separated from cells within 45 minutes of venipuncture. Send serum/plasma in a plastic transport tube. To avoid delays in turnaround time when requesting multiple test on frozen samples, please submit seperate frozen specimens for each test requested.
Stability Requirements
| Temperature | Period |
|---|---|
| Room temperature | 7 days |
| Refrigerated | 7 days |
| Frozen | 7 days |
| Freeze/thaw cycles | Stable x3 |
Reference Range
Golimumab drug level: <0.5 μg/mL
• Result ≥0.5 μg/mL indicates detection of golimumab
• In the presence of serum anti-golimumab antibodies, the golimumab drug level reflects the antibody-unbound (free) fraction of golimumab in serum.
Anti-golimumab antibody: <20 ng/mL
• Result ≥20ng/mL indicates detection of anti-golimumab antibodies.
Storage Instructions
Freeze.
Causes for Rejection
Gross hemolysis, gross lipemia
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 504563 | Golimumab Drug + Antibody | 504564 | Golimumab | ug/mL | 87406-5 | |
| 504563 | Golimumab Drug + Antibody | 504565 | Anti-Golimumab Antibody | ng/mL | 87407-3 | |
| Order Code | 504563 | |||||
| Order Code Name | Golimumab Drug + Antibody | |||||
| Order Loinc | ||||||
| Result Code | 504564 | |||||
| Result Code Name | Golimumab | |||||
| UofM | ug/mL | |||||
| Result LOINC | 87406-5 | |||||
| Order Code | 504563 | |||||
| Order Code Name | Golimumab Drug + Antibody | |||||
| Order Loinc | ||||||
| Result Code | 504565 | |||||
| Result Code Name | Anti-Golimumab Antibody | |||||
| UofM | ng/mL | |||||
| Result LOINC | 87407-3 |
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
|---|---|---|---|---|---|---|
| Reflex 1 | 504108 | Serial Monitoring | 000000 | Serial Monitoring | N/A | |
| Reflex 1 | ||||||
| Order Code | 504108 | |||||
| Order Name | Serial Monitoring | |||||
| Result Code | 000000 | |||||
| Result Name | Serial Monitoring | |||||
| UofM | ||||||
| Result LOINC | N/A | |||||
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
|---|---|---|---|---|---|---|
| Reflex 1 | 504108 | Serial Monitoring | 511958 | 80563-0 | ||
| Reflex 1 | ||||||
| Order Code | 504108 | |||||
| Order Name | Serial Monitoring | |||||
| Result Code | 511958 | |||||
| Result Name | ||||||
| UofM | ||||||
| Result LOINC | 80563-0 | |||||