Test Includes
C-Reactive Protein (CRP), Quantitative; D-Dimer; Neutrophil to Lymphocyte Ratio (NLR), Complete Blood Count (CBC) With Differential and Platelet
Expected Turnaround Time
1 - 2 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Related Documents
Specimen Requirements
Specimen
Serum, plasma, and whole blood
Volume
1 mL serum, 2 mL plasma (sodium citrate), and 4 mL whole blood (EDTA)
Minimum Volume
1 mL serum, 1 mL plasma (sodium citrate), and 4 mL whole blood (Note: This volume does not allow for repeat testing.)
Container
Gel-barrier tube, blue-top (sodium citrate) tube, and lavender-top (EDTA) tube
Collection
Blood should be collected in a blue-top tube containing 3.2% buffered sodium citrate. Evacuated collection tubes must be filled to completion to ensure a proper blood to anticoagulant ratio. The sample should be mixed immediately by gentle inversion at least six times to ensure adequate mixing of the anticoagulant with the blood. A discard tube is not required prior to collection of coagulation samples. When noncitrate tubes are collected for other tests, collect sterile and nonadditive (red-top) tubes prior to citrate (blue-top) tubes. Any tube containing an alternate anticoagulant should be collected after the blue-top tube. Gel-barrier tubes and serum tubes with clot initiators should also be collected after the citrate tubes. Centrifuge and carefully remove the plasma using a plastic transfer pipette, being careful not to disturb the cells.Transfer the plasma into a Labcorp PP transpak frozen purple tube with screw cap (Labcorp No. 49482). Freeze plasma within four hours of blood collection and maintain frozen until tested. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit seperate frozen specimens for each test requested.
Storage Instructions
Frozen: Plasma
Room Temperature: Serum and whole blood (EDTA)
Test Details
Use
Assessment of patients at risk of progession to severe COVID-19 within 7 days from admission
Methodology
See individual test components.
References
Cicculo A, Borghetti A, Dal Verme LZ, et al. Neutrophil-to-lymphocyte ratio and clinical outcome in COVID-19: a report from the Italian front line. Int J Antimicrob Agents. 2020 Aug;56(2):106017.32437920
Gao Y, Li T, Han M, et al. Diagnostic utility of clinical laboratory data determinations for patients with the severe COVID-19. J Med Virol. 2020 Jul;92(7):791-796.32181911
Kerboua KE. NLR: A Cost-effective Nomogram to Guide Therapeutic Interventions in COVID-19. Immunol Invest. 2021 Jan;50(1):92-100.32482134
Liu YP, Li GM, He J, et al. Combined use of the neutrophil-to-lymphocyte ratio and CRP to predict 7-day disease severity in 84 hospitalized patients with COVID-19 pneumonia: a retrospective cohort study. Ann Transl Med. 2020 May;8(10):635.32566572
Tatum D, Taghavi S, Houghton A, Stover J, Toraih E, Duchesne J. Neutrophil-to-lymphocyte ratio and outcomes in Louisiana COVID-19 patients. Shock. 2020 Nov;54(5):652-658.32554992
Yang AP, Liu JP, Tao WQ, Li HM. The diagnostic and predictive role of NLR, d-NLR and PLR in COVID-19 patients. Int Immunopharmacol. 2020 Jul;84:106504.32304994
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 164052 | COVID-19 Triage Panel | 006627 | C-Reactive Protein, Quant | mg/L | 1988-5 | |
| 164052 | COVID-19 Triage Panel | 115206 | D-Dimer | mg/L FEU | 48065-7 | |
| 164052 | COVID-19 Triage Panel | 005025 | WBC | x10E3/uL | 6690-2 | |
| 164052 | COVID-19 Triage Panel | 005033 | RBC | x10E6/uL | 789-8 | |
| 164052 | COVID-19 Triage Panel | 005041 | Hemoglobin | g/dL | 718-7 | |
| 164052 | COVID-19 Triage Panel | 005058 | Hematocrit | % | 4544-3 | |
| 164052 | COVID-19 Triage Panel | 015065 | MCV | fL | 787-2 | |
| 164052 | COVID-19 Triage Panel | 015073 | MCH | pg | 785-6 | |
| 164052 | COVID-19 Triage Panel | 015081 | MCHC | g/dL | 786-4 | |
| 164052 | COVID-19 Triage Panel | 105007 | RDW | % | 788-0 | |
| 164052 | COVID-19 Triage Panel | 015172 | Platelets | x10E3/uL | 777-3 | |
| 164052 | COVID-19 Triage Panel | 015107 | Neutrophils | % | 770-8 | |
| 164052 | COVID-19 Triage Panel | 015123 | Lymphs | % | 736-9 | |
| 164052 | COVID-19 Triage Panel | 015131 | Monocytes | % | 5905-5 | |
| 164052 | COVID-19 Triage Panel | 015149 | Eos | % | 713-8 | |
| 164052 | COVID-19 Triage Panel | 015156 | Basos | % | 706-2 | |
| 164052 | COVID-19 Triage Panel | 115398 | Immature Cells | N/A | ||
| 164052 | COVID-19 Triage Panel | 015909 | Neutrophils (Absolute) | x10E3/uL | 751-8 | |
| 164052 | COVID-19 Triage Panel | 015917 | Lymphs (Absolute) | x10E3/uL | 731-0 | |
| 164052 | COVID-19 Triage Panel | 015912 | Neut/Lymph Ratio | ratio | N/A | |
| 164052 | COVID-19 Triage Panel | 015925 | Monocytes(Absolute) | x10E3/uL | 742-7 | |
| 164052 | COVID-19 Triage Panel | 015933 | Eos (Absolute) | x10E3/uL | 711-2 | |
| 164052 | COVID-19 Triage Panel | 015941 | Baso (Absolute) | x10E3/uL | 704-7 | |
| 164052 | COVID-19 Triage Panel | 015108 | Immature Granulocytes | % | 71695-1 | |
| 164052 | COVID-19 Triage Panel | 015911 | Immature Grans (Abs) | x10E3/uL | 53115-2 | |
| 164052 | COVID-19 Triage Panel | 015945 | NRBC | % | 58413-6 | |
| 164052 | COVID-19 Triage Panel | 015180 | Hematology Comments: | 18314-5 | ||
| 164052 | COVID-19 Triage Panel | 164054 | COVID 19 Triage Panel | N/A |
| Reflex Table for Immature Cells | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 115399 | Immature Cells | 115400 | Bands | % | 35332-6 |
| Reflex Table for Immature Cells | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 115399 | Immature Cells | 115401 | Metamyelocytes | % | 28541-1 |
| Reflex Table for Immature Cells | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 115399 | Immature Cells | 115403 | Myelocytes | % | 26498-6 |
| Reflex Table for Immature Cells | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 115399 | Immature Cells | 115404 | Promyelocytes | % | 26498-6 |
| Reflex Table for Immature Cells | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 115399 | Immature Cells | 115405 | Blasts/blast like cells | % | 26498-6 |
| Reflex Table for Immature Cells | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 115399 | Immature Cells | 115406 | Megakaryocytes | % | 19252-6 |
| Reflex Table for Immature Cells | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 115399 | Immature Cells | 115265 | Other, Lineage Uncertain | % | 55433-7 |
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